Listar por tema "Peak%20profiles%20in%20chromatography%20are%20characterised%20by%20their%20height,%20position,%20width%20and%20asymmetry;%20the%20two%20latter%20depend%20on%20the%20values%20of%20the%20left%20and%20right%20peak%20half-widths.%20Simple%20correlations%20have%20been%20found%20between%20the%20peak%20half-widths%20and%20the%20retention%20times.%20The%20representation%20of%20such%20correlations%20has%20been%20called%20half-width%20plots.%20For%20isocratic%20elution,%20the%20plots%20are%20parabolic,%20although%20often,%20the%20parabolas%20can%20be%20approximated%20to%20straight-lines.%20The%20plots%20can%20be%20obtained%20with%20the%20half-widths/retention%20time%20data%20for%20a%20set%20of%20solutes%20experiencing%20the%20same%20kinetics,%20eluted%20with%20a%20mobile%20phase%20at%20fixed%20or%20varying%20composition.%20When%20the%20analysed%20solutes%20experience%20different%20resistance%20to%20mass%20transfer,%20the%20plots%20will%20be%20solute%20dependent,%20and%20should%20be%20obtained%20with%20the%20data%20for%20each%20solute%20eluted%20with%20mobile%20phases%20at%20varying%20composition.%20The%20half-width%20plots%20approach%20is%20a%20simple%20tool%20that%20facilitates%20the%20prediction%20of%20peak%20shape%20(width%20and%20asymmetry)%20with%20optimisation%20purposes,%20reveal%20the%20interaction%20kinetics%20of%20solutes%20in%20different%20columns,%20and%20characterise%20chromatographic%20columns.%20This%20work%20shows%20half-width%20plots%20for%20different%20situations%20in%20isocratic%20elution,%20including%20the%20use%20of%20different%20flows,%20the%20effect%20of%20temperature,%20the%20modification%20of%20the%20stationary%20phase%20surface%20by%20an%20additive,%20the%20existence%20of%20specific%20interactions%20within%20the%20column,%20and%20the%20comparison%20of%20columns.%20The%20adaptation%20to%20gradient%20elution%20is%20also%20described.%20Previous%20knowledge%20on%20half-width%20plots%20is%20structured%20and%20analysed,%20to%20which%20new%20results%20are%20added."
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